Cell-mediated immune response of human lymphocytes to influenza A/USSR (H1N1) virus infection.

Infect Immun. 1980 March; 27(3): 867–871.
A Lazar and P F Wright
Cell-mediated immunity to influenza A/USSR (H1N1) virus was assessed by measuring transformation response and interferon production by Ficoll-Hypaque-purified peripheral blood lymphocytes from children and adults. Lymphocyte transformation was found to be related to the individual’s previous experience with H1N1 influenza virus. Lymphocyte cultures, obtained from adults who had their last contact with the H1N1 virus over 20 years ago, were able to transform when incubated with H1N1 influenza antigens. This response suggests that influenza virus can induced long-term cell-mediated immunity for periods of at least 20 years. Interferon produced by stimulated lymphocytes was found to be unrelated to previous contact with influenza H1N1 virus; seronegative as well as seropositive individuals were capable of producing interferon in response to viral antigens. The interferon produced was type I.

references

  • Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl. 1968;97:77–89. [PubMed]
  • Cole PJ, Molyneux ME. Lymphocyte reactivity to influenza virus in man. Immunology. 1975 Oct;29(4):749–754. [PubMed]
  • Denman EJ, Denman AM, Greenwood BM, Gall D, Heath RB. Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis. Ann Rheum Dis. 1970 May;29(3):220–231. [PubMed]
  • Dolin R, Murphy BR, Caplan EA. Lymphocyte blastogenic responses to influenza virus antigens after influenza infection and vaccination in humans. Infect Immun. 1978 Mar;19(3):867–874. [PubMed]
  • Epstein Lois B, Stevens David A, Merigan Thomas C. Selective Increase in Lymphocyte Interferon Response to Vaccinia Antigen after Revaccination. Proc Natl Acad Sci U S A. 1972 Sep;69(9):2632–2636. [PubMed]
  • Gerber P, Lucas SJ. In vitro stimulation of human lymphocytes by Epstein-Barr virus. Cell Immunol. 1972 Oct;5(2):318–324. [PubMed]
  • Glass RI, Brann EA, Slade JD, Jones WE, Scally MJ, Craven RB, Gregg MG. Community-wide surveillance of influenza after outbreaks due to H3N2 (A/Victoria/75 and A/Texas/77) and H1N1 (A/USSR/77) influenza viruses, Mercer County, New Jersey, 1978. J Infect Dis. 1978 Nov;138(5):703–706. [PubMed]
  • Gregg MB, Hinman AR, Craven RB. The Russian flu. Its history and implications for this year’s influenza season. JAMA. 1978 Nov 17;240(21):2260–2263. [PubMed]
  • Haahr S, Rasmussen L, Merigan TC. Lymphocyte transformation and interferon production in human mononuclear cell microcultures for assay of cellular immunity to herpes simplex virus. Infect Immun. 1976 Jul;14(1):47–54. [PubMed]
  • Hall CB, Douglas RG, Jr, Simons RL, Geiman JM. Interferon production in children with respiratory syncytial, influenza, and parainfluenza virus infections. J Pediatr. 1978 Jul;93(1):28–32. [PubMed]
  • Jao RL, Wheelock EF, Jackson GG. Production of interferon in volunteers infected with Asian influenza. J Infect Dis. 1970 Apr;121(4):419–426. [PubMed]
  • Jordan GW, Merigan TC. Cell-mediated immunity to varicella-zoster virus: in vitro lymphocyte responses. J Infect Dis. 1974 Nov;130(5):495–501. [PubMed]
  • McIntosh K. Interferon in nasal secretions from infants with viral respiratory tract infections. J Pediatr. 1978 Jul;93(1):33–36. [PubMed]
  • Meguro H, Bryant JD, Torrence AE, Wright PF. Canine kidney cell line for isolation of respiratory viruses. J Clin Microbiol. 1979 Feb;9(2):175–179. [PubMed]
  • Murphy BR, Baron S, Chalhub EG, Uhlendorf CP, Chanock RM. Temperature-sensitive mutants of influenza virus. IV. Induction of interferon in the nasopharynx by wild-type and a temperature-sensitive recombinant virus. J Infect Dis. 1973 Oct;128(4):488–493. [PubMed]
  • Rasmussen LE, Jordan GW, Stevens DA, Merigan TC. Lymphocyte interferon production and transformation after Herpes simplex infections in humans. J Immunol. 1974 Feb;112(2):728–736. [PubMed]
  • Ruben Frederick L, Jackson George G, Gotoff Samuel P. Humoral and Cellular Response in Humans After Immunization with Influenza Vaccine. Infect Immun. 1973 Apr;7(4):594–596. [PubMed]
  • Smith KA, Chess L, Mardiney MR., Jr The characteristics of lymphocyte tritiated thymidine incorporation in response to mumps virus. Cell Immunol. 1972 Dec;5(4):597–603. [PubMed]
  • Waner JL, Budnick JE. Blastogenic response of human lymphocytes to human cytomegalovirus. Clin Exp Immunol. 1977 Oct;30(1):44–49. [PubMed]
  • Welliver RC, Kaul A, Ogra PL. Cell-mediated immune response to respiratory syncytial virus infection: relationship to the development of reactive airway disease. J Pediatr. 1979 Mar;94(3):370–375. [PubMed]

 

www.penyakitmenular.com

Provided By: WWW.PENYAKITMENULAR.COM Supported By: GRoW UP CLINIC JAKARTA Yudhasmara Foundation GRoW UP CLINIC I Jl Taman Bendungan Asahan 5 Bendungan Hilir Jakarta Pusat 10210, phone (021) 5703646 – 085101466102 – 085100466103 GRoW UP CLINIC II MENTENG SQUARE Jl Matraman 30 Jakarta Pusat 10430, Phone (021) 2961425208131592-2012 – 08131592-2013 – 08131592-2012 email : judarwanto@gmail.com http://growupclinic.com Facebook: http://www.facebook.com/GrowUpClinic Twitter: @growupclinic Professional Healthcare Provider “GRoW UP CLINIC” Dr Narulita Dewi SpKFR, Physical Medicine & Rehabilitation curriculum vitae HP 085777227790 PIN BB 235CF967 Clinical – Editor in Chief : Dr Widodo Judarwanto, Pediatrician Editor: Audi Yudhasmara email : judarwanto@gmail.com Mobile Phone O8567805533 PIN BBM 76211048 Komunikasi dan Konsultasi online : twitter @widojudarwanto facebook dr Widodo Judarwanto, pediatrician Komunikasi dan Konsultasi Online Alergi Anak : Allergy Clinic Online Komunikasi dan Konsultasi Online Sulit makan dan Gangguan Berat Badan : Picky Eaters Clinic Komunikasi Profesional Pediatric: Indonesia Pediatrician Online
“GRoW UP CLINIC” Jakarta Focus and Interest on: *** Allergy Clinic Online *** Picky Eaters and Growup Clinic For Children, Teen and Adult (Klinik Khusus Gangguan Sulit Makan dan Gangguan Kenaikkan Berat Badan)*** Children Foot Clinic *** Physical Medicine and Rehabilitation Clinic *** Oral Motor Disorders and Speech Clinic *** Children Sleep Clinic *** Pain Management Clinic Jakarta *** Autism Clinic *** Children Behaviour Clinic *** Motoric & Sensory Processing Disorders Clinic *** NICU – Premature Follow up Clinic *** Lactation and Breastfeeding Clinic *** Swimming Spa Baby & Medicine Massage Therapy For Baby, Children and Teen *** We are guilty of many errors and many faults. But our worst crime is abandoning the children, neglecting the fountain of life.
Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. You should carefully read all product packaging. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider

Copyright © 2015, WWW.PENYAKITMENULAR.COM, Information Education Network. All rights reserved

Tinggalkan Balasan

Isikan data di bawah atau klik salah satu ikon untuk log in:

Logo WordPress.com

You are commenting using your WordPress.com account. Logout / Ubah )

Gambar Twitter

You are commenting using your Twitter account. Logout / Ubah )

Foto Facebook

You are commenting using your Facebook account. Logout / Ubah )

Foto Google+

You are commenting using your Google+ account. Logout / Ubah )

Connecting to %s